They that are no longer in peace with their relatives, obtain no sleep even if they have recourse to well-made beds; nor do they, O king, derive any pleasure from women, or the laudatory hymns of bards and eulogists. Such persons can never practise virtue. Happiness can never be theirs, in this world. Honours can never be theirs, and peace hath no charm for them. Counsels that are for their benefit please them not. They never acquire what they have not, nor succeed in retaining what they have.
In plain words: Vidura tells the king that people who are at war with their own relatives cannot sleep, even in fine beds, and cannot enjoy pleasures or praise. They cannot live rightly, be happy, be respected, or feel peace. They dislike good advice, and they cannot gain new things or keep what they have.