Let us therefore renounce the angry passions of our race and so exert ourselves that we may obtain that perfect beatitude which is beyond the power of the deities of fire, of the sun, of the moon, of wind, of Indra, of the regent of the sea, of the Siddhas of the Rākshasas, of the Daitya-chief, of the serpents, of Kinnaras, of men, or beasts or human weaknesses and which is uninterrupted by various diseases such as fever, eye-disease &c., by hatred, malice, passion or desire.

In plain words: Prahlada urges the boys to give up the angry ways of their demon family. Instead they should seek a perfect happiness that no god, demon or other being can take away. Disease, hatred and desire cannot disturb it either.