One should not, however, act like a fool by giving free indulgence to his senses. Prosperity never resides in one who suffers himself to be tortured by a grief, who is addicted to evil ways, who denies Godhead, who is idle, who hath not his senses under control, and who is divested of exertion. The man that is humble, and who from humility is modest is regarded as weak and persecuted by persons of misdirected intelligence.

In plain words: Don't foolishly give in to every craving. Good fortune stays away from people who drown in grief, have bad habits, deny God, are lazy, lack self-control, or won't make an effort. Sadly, humble and modest people are often seen as weak and picked on by people with bad judgment.