Happiness and misery, plenty and want, gain and loss, life and death, are shared by all in due order. Therefore, he that is self-controlled should neither exult in joy nor repine in sorrow. The six senses are always restless. Through the most predominant one amongst them one’s understanding escapeth in proportion to the strength it assumes, like water from a pot through its holes.

In plain words: Vidura tells King Dhritarashtra that everyone takes turns with joy and sorrow, having plenty and having little, winning and losing, living and dying. So a self-controlled person should not get carried away by joy or crushed by sorrow. The senses are always restless, and whichever one is strongest drains away a person's good sense, like water leaking from a pot with holes.